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Items 1 - 20 of 159
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1:

Modification of the Tet-On regulatory system prevents the conditional-live HIV-1 variant from losing doxycycline-control.

Zhou X, Vink M, Berkhout B, Das AT.

Retrovirology. 2006 Nov 9;3:82.

PMID: 17094796 [PubMed - indexed for MEDLINE]

2:

The genetic stability of a conditional live HIV-1 variant can be improved by mutations in the Tet-On regulatory system that restrain evolution.

Zhou X, Vink M, Klaver B, Verhoef K, Marzio G, Das AT, Berkhout B.

J Biol Chem. 2006 Jun 23;281(25):17084-91. Epub 2006 Apr 20.

PMID: 16627480 [PubMed - indexed for MEDLINE]

3:

Optimization of the doxycycline-dependent simian immunodeficiency virus through in vitro evolution.

Das AT, Klaver B, Centlivre M, Harwig A, Ooms M, Page M, Almond N, Yuan F, Piatak M Jr, Lifson JD, Berkhout B.

Retrovirology. 2008 Jun 5;5:44.

PMID: 18533993 [PubMed - indexed for MEDLINE]

4:

Optimization of the Tet-On system for regulated gene expression through viral evolution.

Zhou X, Vink M, Klaver B, Berkhout B, Das AT.

Gene Ther. 2006 Oct;13(19):1382-90. Epub 2006 May 25.

PMID: 16724096 [PubMed - indexed for MEDLINE]

5:

Strict control of human immunodeficiency virus type 1 replication by a genetic switch: Tet for Tat.

Verhoef K, Marzio G, Hillen W, Bujard H, Berkhout B.

J Virol. 2001 Jan;75(2):979-87.

PMID: 11134311 [PubMed - indexed for MEDLINE]

6:

Construction of a doxycycline-dependent simian immunodeficiency virus reveals a nontranscriptional function of tat in viral replication.

Das AT, Klaver B, Harwig A, Vink M, Ooms M, Centlivre M, Berkhout B.

J Virol. 2007 Oct;81(20):11159-69. Epub 2007 Aug 1.

PMID: 17670816 [PubMed - indexed for MEDLINE]

7:

Viral evolution as a tool to improve the tetracycline-regulated gene expression system.

Das AT, Zhou X, Vink M, Klaver B, Verhoef K, Marzio G, Berkhout B.

J Biol Chem. 2004 Apr 30;279(18):18776-82. Epub 2004 Feb 2.

PMID: 14761948 [PubMed - indexed for MEDLINE]

8:

Improving the safety of a conditional-live human immunodeficiency virus type 1 vaccine by controlling both gene expression and cell entry.

Das AT, Baldwin CE, Vink M, Berkhout B.

J Virol. 2005 Mar;79(6):3855-8.

PMID: 15731280 [PubMed - indexed for MEDLINE]

9:

Conditional virus replication as an approach to a safe live attenuated human immunodeficiency virus vaccine.

Berkhout B, Verhoef K, Marzio G, Klaver B, Vink M, Zhou X, Das AT.

J Neurovirol. 2002 Dec;8 Suppl 2:134-7. Review.

PMID: 12491165 [PubMed - indexed for MEDLINE]

10:

Dox-dependent SIVmac with tetracycline-inducible promoter in the U3 promoter region.

Xiao Y, Kuwata T, Miura T, Hayami M, Shida H.

Virology. 2000 Apr 10;269(2):268-75.

PMID: 10753705 [PubMed - indexed for MEDLINE]

11:

Construction of doxycyline-dependent mini-HIV-1 variants for the development of a virotherapy against leukemias.

Jeeninga RE, Jan B, van den Berg H, Berkhout B.

Retrovirology. 2006 Sep 27;3:64.

PMID: 17005036 [PubMed - indexed for MEDLINE]

12:

In vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies.

Marzio G, Verhoef K, Vink M, Berkhout B.

Proc Natl Acad Sci U S A. 2001 May 22;98(11):6342-7. Epub 2001 May 15.

PMID: 11353837 [PubMed - indexed for MEDLINE]

13:

Improved single-chain transactivators of the Tet-On gene expression system.

Zhou X, Symons J, Hoppes R, Krueger C, Berens C, Hillen W, Berkhout B, Das AT.

BMC Biotechnol. 2007 Jan 19;7:6.

PMID: 17239234 [PubMed - indexed for MEDLINE]

14:

Control over HIV-1 replication by an antibiotic; a novel vaccination strategy with a drug-dependent virus.

Berkhout B, Marzio G, Verhoef K.

Virus Res. 2002 Jan 30;82(1-2):103-8. Review. No abstract available.

PMID: 11885936 [PubMed - indexed for MEDLINE]

15:

A second-site mutation that restores replication of a Tat-defective human immunodeficiency virus.

Verhoef K, Berkhout B.

J Virol. 1999 Apr;73(4):2781-9.

PMID: 10074125 [PubMed - indexed for MEDLINE]

17:

A conditionally replicating HIV-based vector that stably expresses an antiviral shRNA against HIV-1 replication.

Westerhout EM, Vink M, Haasnoot PC, Das AT, Berkhout B.

Mol Ther. 2006 Aug;14(2):268-75. Epub 2006 May 11.

PMID: 16697708 [PubMed - indexed for MEDLINE]

18:

A bidirectional Tet-dependent promotor construct regulating the expression of E1A for tight control of oncolytic adenovirus replication.

Fechner H, Wang X, Picó AH, Wildner J, Suckau L, Pinkert S, Sipo I, Weger S, Poller W.

J Biotechnol. 2007 Jan 20;127(4):560-74. Epub 2006 Sep 27.

PMID: 17083991 [PubMed - indexed for MEDLINE]

19:

Doxycycline-regulated lentiviral vector system with a novel reverse transactivator rtTA2S-M2 shows a tight control of gene expression in vitro and in vivo.

Koponen JK, Kankkonen H, Kannasto J, Wirth T, Hillen W, Bujard H, Ylä-Herttuala S.

Gene Ther. 2003 Mar;10(6):459-66.

PMID: 12621450 [PubMed - indexed for MEDLINE]

20:

Use of the tetracycline-controlled transcriptional silencer (tTS) to eliminate transgene leak in inducible overexpression transgenic mice.

Zhu Z, Ma B, Homer RJ, Zheng T, Elias JA.

J Biol Chem. 2001 Jul 6;276(27):25222-9. Epub 2001 Apr 30.

PMID: 11331286 [PubMed - indexed for MEDLINE]

Items 1 - 20 of 159
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