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HIV-1 Nef: at the crossroads.
Foster JL, Garcia JV
Retrovirology 2008, 5:84
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A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex.
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Human immunodeficiency virus type 1 Nef protein targets CD4 to the multivesicular body pathway.
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Effective downregulation of HLA-A*2 and HLA-B*57 by primary human immunodeficiency virus type 1 isolates cultured from elite suppressors.
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